A pill that can help
you achieve clearer skin

Treat plaque psoriasis differently

Treat psoriatic arthritis differently

FOR US AUDIENCES ONLY

1-844-4otezla $0 co-pay* offer

Otezla for moderate to severe
plaque psoriasis

Otezla for psoriatic arthritis

SEE MORE

*Certain restrictions apply. *Certain restrictions apply; eligibility not based on income.

APPROVED USES

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of having diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla include diarrhea, nausea, vomiting, upper respiratory tract infection, runny nose, sneezing, or congestion, abdominal pain, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for Full Prescribing Information.

Results with Otezla

Just as psoriasis presents differently in different people, results with Otezla will vary. If Otezla works for you, it’s likely you’ll notice your skin getting clearer over time.

75% clearer skin

Studies showed that after just 4 months on Otezla, a 75% reduction in plaque psoriasis is achievable for some people. See additional efficacy results

See more benefits of Otezla

Before & after photos

Otezla has been proven to improve moderate to severe plaque psoriasis symptoms in commonly affected areas like the elbows, knees, lower back, and scalp. Below are pictures of people with plaque psoriasis, before and during treatment with Otezla.

Actual Otezla patients. Not everyone responds to Otezla, and those who do respond may respond differently.

Back

Picture of Otezla results on back affected with psoriasis after treatment

Legs

Picture of Otezla results on legs affected with psoriasis after treatment

Elbow

Picture of Otezla results on elbows affected with psoriasis after treatment

Hand

Picture of Otezla results on hands affected with psoriasis after treatment

Scalp

Picture of Otezla results on scalp affected with psoriasis after treatment

Ear

Picture of Otezla results on ear affected with psoriasis after treatment

Nail

Picture of Otezla results on nails affected with psoriasis after treatment

Common side effects

The most common side effects of Otezla were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.

The majority of people reporting nausea and diarrhea did so within the first 2 weeks of treatment and these side effects tended to go away over time without stopping Otezla. Tell your doctor if any of these occur.

Learn more about side effects

Want to know more
about Otezla?

Sign up now

Gotezla

Want help tracking your progress?

Get the free Otezla app

SEE MORE

*Certain restrictions apply. *Certain restrictions apply; eligibility not based on income.

APPROVED USES

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of having diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla include diarrhea, nausea, vomiting, upper respiratory tract infection, runny nose, sneezing, or congestion, abdominal pain, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for Full Prescribing Information.

Important Safety Information

See more

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of having diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

You are now leaving otezla.com and going to

The content of the linked site is the sole responsibility of the site provider. Celgene Corporation does not control or endorse this third-party website.

Click "OK" to proceed or "CANCEL" to return to otezla.com.

Ok Cancel

You are now leaving otezla.com and going to

Are you sure you want to do this?

Yes No

You are now leaving otezla.com for plaque psoriasis and going to otezla.com for psoriatic arthritis

Click "OK" to proceed or "CANCEL" to return.

Ok Cancel

You are now leaving otezla.com for psoriatic arthritis and going to otezla.com for plaque psoriasis

Click "OK" to proceed or "CANCEL" to return.

Ok Cancel